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Body Recomposition: CJC-1295 + Ipamorelin for Simultaneous Fat Loss and Muscle Gain

  • Writer: Peter Young
    Peter Young
  • Dec 29, 2025
  • 3 min read

Fit woman


You've been told it's impossible. Pick one - lose fat or build muscle. The body doesn't do both at the same time. You need a caloric surplus for muscle growth, a caloric deficit for fat loss. Choose your priority.


Except your body doesn't actually work that way when growth hormone optimisation removes the metabolic limitations, forcing that choice.


The CJC-1295 + Ipamorelin combination creates the dual-pathway growth hormone optimisation that makes simultaneous fat loss and muscle gain physiologically achievable.


Why Traditional Recomposition Fails


Body recomposition - losing fat whilst building muscle - requires specific metabolic conditions that normal physiology doesn't readily support.

You need adequate protein synthesis for muscle growth. You need effective fat mobilisation for fat loss. You need nutrient partitioning, directing incoming calories toward muscle rather than storage.


Without optimised growth hormone, these processes compete with each other. Caloric deficits required for fat loss limit protein synthesis. Muscle building requires sufficient energy availability to prevent aggressive fat mobilisation.

Most people end up choosing between aggressive cutting, losing muscle, and a building phase that leads to fat accumulation. The simultaneous improvement remains elusive.


How Optimised GH Changes the Equation


Growth hormone optimisation creates metabolic conditions supporting simultaneous fat loss and muscle gain:


Enhanced protein synthesis from pulsatile GH spikes supports muscle building even in caloric deficits. The anabolic signalling overrides deficit limitations.


Increased lipolysis from sustained GH elevation mobilises stored fat for energy, allowing the body to pull from fat stores whilst supporting muscle tissue.


Improved nutrient partitioning ensures that incoming calories are preferentially directed to muscle tissue rather than to fat storage.


Preserved lean mass during deficits as GH's anti-catabolic effects protect muscle tissue from breakdown.


The Dual-Pathway Advantage


CJC-1295 + Ipamorelin creates optimal conditions for recomposition through complementary mechanisms.


CJC-1295's sustained elevation maintains continuous lipolytic signalling throughout the day, keeping fat mobilisation active whilst providing consistent anabolic support, preventing muscle catabolism.


Ipamorelin's targeted pulses produce concentrated GH spikes that trigger maximal protein synthesis. Timing these around training and overnight recovery optimises muscle-building signalling.


Together, they create both the sustained fat-burning environment and the pulsatile muscle-building signals necessary for simultaneous improvement.


The Recomposition Timeline


Weeks 1-2: Initial metabolic shift. Improved recovery, slight increases in muscle fullness, and early fat mobilisation.


Weeks 3-4: Visible changes emerge. Muscle definition improves as subcutaneous fat decreases. Strength is maintained or increased despite fat loss.


Weeks 4-8: Substantial recomposition producing physique changes. Simultaneous fat loss and muscle gain become undeniable. Scale weight may change minimally whilst appearance transforms significantly.


Weeks 8-12: Comprehensive transformation achieving body composition improvements that diet and training alone struggle to produce.


Nutritional Strategy


Recomposition with optimised GH doesn't require extreme dieting. Most users maintain moderate deficits (10-20% below maintenance) or even maintenance calories whilst achieving simultaneous improvements.


High protein intake (2-2.5g per kg bodyweight) ensures adequate substrate for muscle protein synthesis. Carbohydrates around training support performance and recovery.


The metabolic advantages from GH optimisation mean you're not fighting extreme hunger whilst pursuing fat loss. Body composition improvements occur through enhanced metabolic efficiency rather than aggressive restriction.


Training Considerations


Resistance training remains essential. GH optimisation creates conditions that support muscle growth; training provides the stimulus that triggers that growth.


Progressive overload continues driving adaptation. The difference: recovery capacity increases, allowing higher training frequencies without overtraining. Strength progression continues or accelerates despite fat loss that would typically compromise performance.


Real-World Results


Users consistently report physique transformations that don't match typical cutting or bulking patterns:


Scale weight drops 5-8kg whilst strength increases across all major lifts. Waist circumference decreases by 3-5 inches whilst arm and shoulder measurements increase. Body fat percentage drops by 5-8%, whilst lean mass increases by 2-4kg.


These simultaneous improvements reflect genuine recomposition.


Strategic Enhancement


For maximum recomposition effects, many users add complementary compounds:


CJC + Ipamorelin + AOD-9604 enhances fat mobilisation through additional lipolytic pathways.


CJC + Ipamorelin + BPC-157 + TB-500 provides comprehensive recovery support, enabling greater training stimulus.


The Recomposition Reality


Simultaneous fat loss and muscle gain isn't impossible - it's hormonally limited under normal conditions. Growth hormone optimisation through CJC-1295 + Ipamorelin removes those limitations.


Achieve body recomposition with CJC-1295 + Ipamorelin at Fragment and experience physique transformation beyond traditional approaches.


Sometimes the impossible becomes achievable when you optimise the biology controlling it.

 
 
 

3 Comments

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Bangbando
Jan 06
Rated 5 out of 5 stars.

Keen to try, thanks for the well written article.

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Mark42
Jan 05
Rated 5 out of 5 stars.

Super effective combo. been using it since last year.

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Steve B
Jan 05
Rated 5 out of 5 stars.

Heard all good things about these.

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