Five Fast Facts: Ipamorelin

Your Saturday morning peptide primer - everything you need to know in five quick points.

What It Is

Ipamorelin is a selective growth hormone secretagogue that triggers targeted pulses of growth hormone from your pituitary gland. Think of it as a precise biological switch that creates natural growth hormone releases on demand, mimicking the body's own pulsatile patterns without the side effects associated with less selective compounds. It's designed to enhance recovery and body composition through optimised growth hormone timing.

How It Works

Ipamorelin works by binding to ghrelin receptors in your pituitary gland, triggering a controlled release of growth hormone. Unlike other compounds that flood your system indiscriminately, Ipamorelin creates clean, targeted pulses that closely resemble your body's natural rhythm. It doesn't affect cortisol, prolactin, or other hormones - just growth hormone. This selectivity means you can enjoy the benefits of enhanced growth hormone without experiencing unwanted hormonal disruptions.

What It Does

This peptide provides targeted recovery and benefits for body composition. Users report enhanced muscle recovery between training sessions, improved sleep quality with deeper, more restorative rest, better fat loss whilst maintaining muscle mass, increased energy and vitality throughout the day, and improved skin quality and appearance. It's particularly effective when combined with CJC-1295 for comprehensive growth hormone optimisation, providing both sustained elevation and targeted pulses.

How To Use It

Ipamorelin is administered via subcutaneous injection at 200-300mcg once daily in the abdominal area around the belly button or love handles. The compound comes as a lyophilised powder that's reconstituted with sterile water and stored in the refrigerator. Most users inject before bed to enhance overnight recovery and growth hormone release. However, it can be timed around workouts for targeted recovery support.

Who It's For

Ipamorelin is ideal for anyone seeking targeted recovery enhancement and body composition improvement. It's particularly valuable for athletes seeking faster recovery between training sessions, individuals over 30 experiencing declining energy and slower recovery, those struggling with sleep quality or waking up feeling unrested, or anyone looking to improve body composition while maintaining muscle mass. It's commonly stacked with CJC-1295 for synergistic effects.

The Bottom Line

Ipamorelin offers precise growth hormone optimisation without the hormonal disruptions of less selective compounds. Its ability to create clean, targeted growth hormone pulses makes it ideal for strategic timing around recovery needs—whether that's overnight repair, post-workout recovery, or daily vitality enhancement. Most users notice improved recovery and sleep quality within the first week of consistent use.

Ready to experience targeted recovery enhancement? Shop Ipamorelin at Fragment and discover what optimised growth hormone pulses feel like.