Five Fast Facts: PT-141

Your Saturday morning peptide primer - everything you need to know in five quick points.

What It Is

PT-141, also known as Bremelanotide, is a melanocortin receptor agonist that enhances sexual desire and arousal through direct action on the central nervous system. Unlike compounds that work through vascular mechanisms, PT-141 affects actual libido and willingness at the brain level - addressing the psychological and neurological aspects of sexual function rather than just the physical plumbing. It's effective for both men and women, making it one of the few compounds that genuinely enhances female sexual desire and arousal.

How It Works

PT-141 works by activating melanocortin receptors in the brain, particularly MC3R and MC4R, which play crucial roles in sexual arousal and desire. These receptors influence dopamine and other neurotransmitter pathways involved in motivation, reward, and sexual behaviour. The compound crosses the blood-brain barrier to directly affect the areas of your brain responsible for sexual desire, creating genuine arousal rather than just mechanical function. This central nervous system action is why it enhances actual wanting and desire, not just physical capability.

What It Does

This peptide delivers genuine enhancement of sexual desire and arousal for both men and women. Users report increased libido and genuine interest in sexual activity, enhanced arousal and sensitivity during intimacy, improved spontaneity without needing to time dosing precisely, stronger emotional and psychological engagement during sex, and restored sexual desire that had declined due to stress, age, or other factors. It's particularly valuable for addressing low libido rather than erectile dysfunction specifically. However, men report improved function as a secondary benefit of increased arousal.

How To Use It

PT-141 is administered via subcutaneous injection at 2mg, typically 1-2 hours before anticipated sexual activity, though effects can last 6-12 hours or longer. The compound comes as a lyophilised powder that's reconstituted with sterile water and stored in the refrigerator. Most users inject in the abdominal area around the belly button or love handles.

Who It's For

PT-141 is ideal for anyone experiencing reduced libido or sexual desire rather than purely physical dysfunction. It's particularly valuable for women seeking genuine enhancement of sexual desire and arousal, men whose sexual issues stem from low libido rather than vascular problems, couples wanting to enhance intimacy and spontaneity, or anyone whose sexual desire has declined due to stress, age, or relationship factors. It's the compound of choice when the problem is "I'm not interested" rather than "my body won't cooperate."

The Bottom Line

PT-141 represents a fundamentally different approach to sexual enhancement - it addresses desire and arousal at the brain level rather than just vascular function. This makes it effective for both men and women, and particularly valuable for addressing low libido that other compounds don't touch. The effects are a genuine enhancement of wanting and desire, not just mechanical function. Users report restored spontaneity and enjoyment in their intimate lives, with effects that feel natural rather than forced. Start with conservative doses to assess individual response.

Ready to enhance genuine desire and arousal? Shop PT-141 at Fragment and discover what central nervous system sexual enhancement feels like.