The Old Injury Reset: Finally Healing What Never Healed Right the First Time with BPC-157 & TB-500
- Peter Young

- Oct 17
- 4 min read

That ankle you sprained playing football ten years ago still swells up after a long day. The shoulder you hurt moving house five years back never regained full range of motion. The knee injury from that skiing accident "healed," but it clicks and aches whenever you go down stairs. You've learnt to work around these limitations, modifying activities, avoiding specific movements, and accepting reduced function as your new normal.
The doctors told you everything healed fine. The scans came back clear. Physiotherapy helped initially, but progress plateaued. You're left with injuries that technically healed but never feel quite right - lingering stiffness, reduced strength, occasional pain that flares up unpredictably.
Here's what nobody explained: healing and healing properly are two very different things. Your body closed the wound, but it may have done so with poor tissue quality, excessive scar tissue, and structural weaknesses that persist.
The "Good Enough" Healing Problem
When you get injured, your body's primary goal is survival and the restoration of basic function— not optimal healing. It wants to close the wound, stabilise the area, and get you moving again as quickly as possible. This evolutionary priority for speed over quality often results in healing that's "good enough" to survive but far from ideal for long-term function.
The body lays down scar tissue rapidly to bridge damaged areas. This scar tissue is structurally different from the original tissue—less organised, less flexible, and less intense. Collagen fibres align randomly rather than in functional patterns. Blood vessel formation may be incomplete, leaving the area with reduced circulation.
For many injuries, healing stops at this "good enough" stage. The acute pain resolves, function partially returns, and life moves on. But the underlying tissue quality remains compromised, creating problems that persist for years or decades.
Why Old Injuries Stay Problematic
Old injuries that never healed properly create persistent problems through several mechanisms. The scar tissue formed during rapid healing is less flexible and more prone to re-injury. It restricts the range of motion and creates compensatory movement patterns that stress other areas.
Poor initial healing often results in incomplete vascularisation—the injured area never develops an adequate blood vessel network to support normal function. This leaves the tissue metabolically compromised, healing slowly when stressed.
The inflammatory processes that should have resolved completely often persist at low levels, creating chronic inflammation that prevents proper healing whilst causing ongoing discomfort. Additionally, poorly healed tissues usually form adhesions—abnormal connections between structures that restrict movement and disrupt normal biomechanics.
The Tissue Remodelling Solution
What old injuries need isn't more rest or conventional rehabilitation—they need comprehensive tissue remodelling. The poorly organised scar tissue needs to be broken down and rebuilt properly. Blood vessel networks need to be enhanced. Chronic inflammation needs to be resolved.
This is where the combination of BPC-157 and TB-500 becomes particularly powerful. These peptides actively promote tissue remodelling, breaking down poor-quality scar tissue whilst building properly organised, functional tissue in its place.
BPC-157: The Foundation Rebuilder
BPC-157 at 400-1,000mcg daily addresses the chronic inflammation and poor vascularisation that keep old injuries problematic. This peptide promotes the formation of new blood vessels, bringing fresh nutrients and oxygen to areas that have been metabolically compromised for years.
For old injuries, BPC-157's anti-inflammatory effects prove crucial. It reduces chronic low-grade inflammation whilst preserving the beneficial inflammatory signals necessary for tissue remodelling. This rebalancing often provides the reset that stalled healing needs to resume.
TB-500: The Tissue Reorganiser
TB-500 at 300-1,000mcg daily provides the cellular guidance necessary for proper tissue restructuring. This peptide enhances the migration of repair cells to damaged areas. It promotes the breakdown of poorly organised scar tissue whilst supporting the formation of properly aligned, functional tissue.
For old injuries that healed with excessive or poorly organised scar tissue, TB-500's remodelling effects prove transformative. It helps break down the rigid, inflexible scar tissue that restricts movement whilst building more organised, functional tissue.
The compound also promotes proper collagen alignment: rather than the random, tangled collagen fibres characteristic of scar tissue, it supports the organised, parallel alignment that gives healthy tissue its strength and flexibility.
The Synergistic Remodelling Effect
BPC-157 creates the anti-inflammatory, well-vascularised environment necessary for tissue remodelling, whilst TB-500 provides the cellular guidance and structural reorganisation that transforms poor-quality tissue into functional tissue.
As chronic inflammation resolves and blood flow improves, TB-500's remodelling effects work more effectively. As tissue structure improves and adhesions break down, BPC-157's healing-promoting effects create better-quality replacement tissue.
The Protocol
Both peptides are administered via subcutaneous injection in the abdominal area once daily. The combination works systemically throughout the body, targeting areas of poor tissue quality regardless of where the original injuries occurred.
Many users continue the protocol for 8-12 weeks, giving the tissue remodelling process adequate time to completely restructure poorly healed areas.
The Healing Timeline
Users typically experience progressive improvement as tissue remodelling occurs:
Week 1-2
Reduced pain and inflammation as chronic processes begin resolving and blood flow improves.
Week 3-4
Improved range of motion and reduced stiffness as adhesions break down and tissue flexibility increases.
Week 4-8
Progressive strength gains and functional improvement as tissue quality improves.
Week 8-12
Comprehensive healing with restored function that often exceeds pre-injury levels.
Real-World Transformations
Users consistently report breakthrough improvements in old injuries they'd accepted as permanent limitations. Ankles that have been unstable for years regain stability. Shoulders that lost range of motion years ago suddenly move freely. Knees that clicked and ached become quiet and pain-free.
Many users report that the healed tissue feels stronger and more resilient than it did even before the original injury, reflecting the comprehensive remodelling that occurred.
The Second Chance
Old injuries don't have to be permanent limitations. When initial healing was incomplete or of poor quality, comprehensive tissue remodelling can restructure damaged areas into functional, resilient tissue that restores full capability.
The BPC-157 and TB-500 combination offers the most effective approach to tissue remodelling available, addressing both the metabolic dysfunction and structural problems that keep old injuries symptomatic for years.
Give your old injuries a second chance with BPC-157 + TB-500 at Fragment and discover what happens when tissue is finally allowed to heal properly rather than just "good enough."
Sometimes fixing old problems isn't about managing symptoms—it's about rebuilding tissue the way it should have healed the first time.

Great info guys. Just what i was looking for.